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Laboratory Findings

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Patients with asymptomatic PHPT typically have laboratory values similar to, but somewhat milder, than those with symptomatic PHPT. Serum total and ionized calcium may be high-normal or mildly increased [25]. The serum phosphate level is usually low-normal or mildly decreased, in conjunction with normal serum creatinine. Intact PTH, measured by the second generation 2-site immunoradiometric assay or immunochemiluminometric assays, or the newer third generation intact assay, is mildly increased or inappropriately high-normal for the level of serum calcium [25]. Serum 1,25-dihydroxyvitamin D levels may be high-normal or mildly increased, with serum 25-hydroxyvitamin D levels usually low-normal. In up to 30% of patients, 24-h urinary calcium excretion may be increased.

Parathyroid Disorders

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