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Sun et al. [27] reviewed the experience with PHPT at a single regional hospital in China between 2005 and 2016, and reported that 73.1% of the 260 patients documented remained symptomatic, but that 27.9% were asymptomatic. The number of patients with symptomatic PHPT increased by 2.5-fold from 2005 to 2016, whereas the number of patients with asymptomatic PHPT increased by up to 3-fold over the same interval.