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Retinopathy of Prematurity

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A recent RCT in Canada has been presented in abstract form based on infants with a 100% base diet of HM but randomized to a standard CM-based HM fortifier or a HM-based HM fortifier. The group exposed to the CM fortifier had a significant 6-fold increase in potentially blinding retinopathy of prematurity. In all, at least 7 further studies (5 of them included in a systematic review) showed collectively in around 4,000 subjects a major increase in retinopathy of prematurity with CM exposure compared to EHM [23, 28].

Human Milk: Composition, Clinical Benefits and Future Opportunities

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