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This work was supported by grants from Canadian Institutes of Health Research (CIHR) (No. 106634), the Société des médecins de l’Université de Sherbrooke and the Research Center on Aging of the CIUSSS-CHUS, Sherbrooke, by the Polish Ministry of Science and Higher Education statutory grant 02-0058/07/262 to J.M.W., and by Agency for Science Technology and Research (A*STAR JCO 1434m00115).