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These models have been used to evaluate antimicrobial therapy (mainly oral healthcare products) on oral biofilms in general. Defined microorganisms or saliva as the microcosm source are used. Biofilms are generally formed on glass or hydroxyapatite (HA) disks, in part coated with saliva (Table 1).

Table 1. Examples of biofilm models with a more general focus on the therapy of oral diseases

Table 2. Biofilm models with focus on the therapy and the prevention of caries