Читать книгу Spectrums of Amyotrophic Lateral Sclerosis - Группа авторов - Страница 37

Despite the number of genes associated with ALS, a very low percentage of patients carry a variant in one of these genes. As many as 30% of familial and 90% of sporadic ALS cases can be deemed as “no known genetic cause” [4] – either their disease was caused primarily by environmental factors, or they carry a not‐yet‐identified causal variant (or variants).