Читать книгу The Esophagus - Группа авторов - Страница 145

The LES is tonically closed at rest and maintains a basal resting pressure. The sphincter must relax and open to allow the esophageal bolus to pass into the stomach and to permit retrograde passage with belching and vomiting. LES relaxation occurs with virtually all swallows, even when peristalsis fails to occur. Similarly, distention in the esophagus and secondary peristalsis are associated with LES relaxation. The interactive central and peripheral mechanisms producing the relaxation are related to the mechanisms involved with the production of primary and secondary peristalsis [332, 333].