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Benign tumors Papilloma

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Squamous papillomas are uncommon benign mucosal tumors in the esophagus. These lesions consist histologically of a central fibrovascular core with multiple digit‐like projections covered by hyperplastic squamous epithelium. Papillomas usually appear on double‐contrast esophagography as small, sessile polyps with a smooth or slightly lobulated contour [115]. Occasionally, papillomas are difficult to distinguish from small esophageal cancers on the basis of the radiographic findings (Figure 6.58), so biopsy or resection of the lesions may be required. Some patients can have innumerable papillomas in the esophagus, a rare entity known as esophageal papillomatosis [116].

The Esophagus

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