Читать книгу Genetic Disorders and the Fetus - Группа авторов - Страница 76

Initially, PGT was justified only for high‐risk pregnancies. Maternal age was not expected to be an indication for such early testing, initially being considered even a contraindication to PGT. However, the development and improvement of the methods for sampling and genetic analysis have made use of PGT for chromosomal disorders a reality. Despite continuing discussion of the impact of PGT‐A, it is used routinely worldwide as a tool in assisted reproduction technologies, especially for improving the effectiveness of IVF in poor‐prognosis patients, particularly in carriers of chromosomal rearrangements. As a result, the majority of PGT cycles are still done for PGT‐A.^21–25