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Agunbiade. F. O and Moodley. B (2014). Pharmaceuticals as emerging organic contaminants in Umgeni River water system, Kwazulu-Natal South Africa. Environ Monit Assess 186: 7273–7291.

Aminot. Y, Fuster. L, Pardon. P, Menach. K. L and Budzinski. H (2018). Suspended solids moderate the degradation and sorption of wastewater derived pharmaceuticals in estuarine waters. Science of the total environment 612: 39–48.

Apul, O.G., Rowles III, L.S., Khalid, A., Karanfil, T., Richardson, S.D. and Saleh, N.B., 2020. Transformation potential of cannabinoids during their passage through engineered water treatment systems: A perspective. Environment International, 137, p.105586.

Arnold, K.E., Boxall, A.B.A., Brown, A.R., Cuthbert, R.J., Gaw, S., Hutchinson, TH, Jobling, S., Madden, J.C., Metcalfe, C.D., Naidoo, V., Shore, R.F., Smits, J.E., Taggart, M.A., Thompson, H.M., Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems. Biol. Lett. 9, 20130492, 2013. doi:10.1098/rsbl.2013.0492

Atanasov, A.G., Waltenberger, B., Pferschy-Wenzig, A-M., Linder, T., Wawrosch, C., Uhrin, P., Temml, V. et al., Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnol. Adv. 33(8), 1582–1614, 2015. doi:10.1016/j.biotechadv.2015.08.001

aus der Beek, T. F.A. Weber, A. Bergmann, S. Hickmann, I. Ebert, A. Hein, A. Küster, Pharmaceuticals in the environment-Global occurrences and perspectives, Environ. Toxicol. Chem. 35 (2016) 823–835. https://doi.org/10.1002/etc.3339.

Badejo, M.A., 2000b. Pesticide pollution in aquatic ecosystems in Nigeria and some African countries. In: Badejo, M.A., Van Straalen, N.M. (Eds.), Pollutants and their Effects on Terrestrial and Aquatic Ecosystems. College Press, Ibadan, pp. 43–51.

Bagnis. S, Fitzsimons. M, Snap. J, Tappin. A and Comber. S (2018). Sorption of active pharmaceutical ingredients in untreated wastewater effluent and effect of dilution in freshwater: Implication of an “impact zone” environment risk assessment approach. Science of the total environment 624: 333–341.

Bartros, M., Peñeulas, J., Pharmaceuticals and personal-care products in plants. Trends Plant Sci. 22(3), 194–203, 2017. doi:10.1016/j.tplants.2016.12.010

Bercu, J.P. N.J. Parke, J.M. Fiori, R.D. Meyerhoff, Human health risk assessments for three neuropharmaceutical compounds in surface waters, Regul. Toxicol. Pharmacol. (2008). https://doi.org/10.1016/j.yrtph.2008.01.014.

Boobis, A., Brown, P., Cronin, M.T.D., Edwards, J., Galli, C.L., Goodman, J., Jacobs, A., Kirkland, D., Luijten, M., et al., Origin of the TTC values for compounds that are genotoxic and/or carcinogenic and an approach for their re-evaluation. Critic. Rev. Toxicol. 47(8), 710-32. doi:10.1080/10408444.2017.1318822

Bottoni, P., Caroli, S., Caracciolo, A.B., Pharmaceuticals as priority water contaminants. Toxicol. Environ. Chem. 92(3), 549-565, 2010. doi:10.1080/02772241003614320

Bound, J.P., Voulvoulis, N., Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United Kingdom. Environ. Health Perspect. 113(12), 1705–1711, 2005.

Boxall, A.B.A., The environmental side effects of medication. EMBO Rpt. 5(12), 1110-1116, 2004. doi:10.1038/sj.embor.7400307

Brodin, T., Piovano, S., Fick, J., Klaminder, J., Heynen, M., Jonsson, M., Ecological effects of pharmaceuticals in aquatic systems - impacts through behavioural alterations. Phil. Trans. R. Soc. B. 369, 20130580, 2014. doi:10.1098/rstb.2013.0580

Brooks, B.W., Foran, C.M., Richards, S.M., Weston, J., Turner, P.K., Stanely, J.K., Solomon, K.R. et al., Aquatic ecotoxicology of fluoxetine. Toxicol. Lett. 42, 169–183, 2003. doi:10.1016/S0378-427(03)00066-3

Brown. S., Kennedy, L., Cullington, M., Mihle, A., Lono-Batura, M., Relating pharmaceuticals and personal care products in bisolids to home exposure. Urban Agric. Reg. Food Syst. 4, 180005, 2019. doi:10.2134/urbanag2018.12.0005

Bruce, G.M. R.C. Pleus, S.A. Snyder, Toxicological relevance of pharmaceuticals in drinking water, Environ. Sci. Technol. (2010). https://doi.org/10.1021/es1004895.

Bu, Q., Shi, X., Yu, G., Huang, J., Wang, B., Assessing the the persistence of pharmaceuticals in the aquatic environment: challenges and needs. Emerg. Contaminants 2, 145–147, 2016. doi:10.1016/j.emcon.2016.05.003

Carter, L.J., Chefetz, B., Adbeen, Z., Boxall, A.B.A., Emerging investigator series: towards a framework for establishing the impact of pharmaceuticals in wastewater irrigation systems on agro-ecosystems and human health. Environ. Sci. Processes Impacts. 21, 605, 2019. doi:10.1039/c9em00020h

Chen Z., Zhang W., Wang D., Ma T., Bai R. (2015) Enhancement of activated sludge dewatering performance by combined composite enzymatic lysis and chemical re-flocculation with inorganic coagulants: Kinetics of enzymatic reaction and reflocculation morphology. Water Research 83: 367–376.

Christensen, F.M. Pharmaceuticals in the environment - A human risk?, Regul. Toxicol. Pharmacol. 28, 212–221, (1998). https://doi.org/10.1006/rtph.1998.1253.

Christou, A. P. Karaolia, E. Hapeshi, C. Michael, D. Fatta-Kassinos, Long-term wastewater irrigation of vegetables in real agricultural systems: Concentration of pharmaceuticals in soil, uptake and bioaccumulation in tomato fruits and human health risk assessment, Water Res. (2017). https://doi.org/10.1016/j.watres.2016.11.033.

Colburn A., Vogler R.J., Patel A., Bezold M., Craven J., Liu C., Bhattacharyya D. (2019) Composite Membranes Derived from Cellulose and Lignin Sulfonate for Selective Separations and Antifouling Aspects. Nanomaterials 9: 867; doi:10.3390/nano9060867.

Contardo-Jara, V., Lorenz, C., Pflugmacher, S., Nützmann, G.,, Kloas W., Wiegand, C., Exposure to human pharmaceuticals Carbamazepine, Ibuprofen and Bezafibrate causes molecular effects in Dreissena polymorpha. Aquat. Toxicol. 105, 428–437, 2011. doi:10.1016/j.aquatox.2011.07.017

Couto, C.F. A.V. Santos, M.C.S. Amaral, L.C. Lange, L.H. de Andrade, A.F.S. Foureaux, B.S. Fernandes, Assessing potential of nanofiltration, reverse osmosis and membrane distillation drinking water treatment for pharmaceutically active compounds (PhACs) removal, J. Water Process Eng. (2020). https://doi.org/10.1016/j.jwpe.2019.101029.

Cunha D.L., Kuznetsov A., Araujo J.R., Neves R.S., Archanjo B.S., Canela M.C., Marques M. (2019) Optimization of Benzodiazepine Drugs Removal from Water by Heterogeneous Photocatalysis Using TiO₂/Activated Carbon Composite. Water Air Soil Pollut 230:141. ²

Daneshvar. A, svanfelt. J, Kronberg. L and Weyhenmeyer. G. A (2010). Winter accumulation of acidic pharmaceuticals in Swedish River. Environ Sci Pollut Res 17:908–916.

Daughton, C.G., Pharmaceuticals and the environment (PiE): Evolution and impact o f the published literature revealed by bibliometric analysis. Sci. Tot. Environ. 562, 391-426, 2016. doi: 0.1016/j.scitotenv.2016.03.109

Daughton, C.G., Ruhoy, I.S., Environmental footprint of pharmaceuticals: the significance of factors beyond direct excretion to sewers. Environ. Toxicol. Chem. 28(2), 2495–2521, 2009.

Daughton, C.G., Ternes, T.A., Pharmaceuticals and personal care products in the environment: Agents of subtle change? Environ. Health. Perspect. 107(6), 907–938, 1999.

De Gisi S., Lofrano G., Grassi M., Notarnicola M. (2016) Characteristics and adsorption capacities of low-cost sorbents for wastewater treatment: A review. Sustainable Materials and Technologies 9: 10–40.

de Jesus Gaffney, V. C.M.M. Almeida, A. Rodrigues, E. Ferreira, M.J. Benoliel, V.V. Cardoso, Occurrence of pharmaceuticals in a water supply system and related human health risk assessment, Water Res. 72 (2015) 199–208. https://doi.org/10.1016/j.watres.2014.10.027.

de Jongh, C.M. P.J.F. Kooij, P. de Voogt, T.L. ter Laak, Screening and human health risk assessment of pharmaceuticals and their transformation products in Dutch surface waters and drinking water, Sci. Total Environ. 427–428 (2012) 70–77. https://doi.org/10.1016/j.scitotenv.2012.04.010.

Deo, R.P., Pharmaceuticals in the surface water of the USA: A review. Curr. Environ. Health Rpt. 1, 113-122, 2014. doi:10.1007/s40572-014-0015-y

Du. J, Fan. Y, and Qian. X (2015). Occurrence and behaviour of pharmaceuticals in sewage treatment lants in eastern China. Font Environ. Sci. Eng. 9(4): 725–730.

Fabbri, E., Franzellitti, S., Human pharmaceuticals in the marine environment: focus on exposure and biological effect in animal species. Environ. Toxicol. Chem. 35(4), 799-812, 2016. doi:10.1002/etc.3131

Fantuzzi, G., Aggazzotti, G., Righi, E., Predieri, G., Castiglioni, S., Riva, F. and Zuccato, E., 2018. Illicit drugs and pharmaceuticals in swimming pool waters. Science of the Total Environment, 635, pp.956–963.

Farshad, A, A., Enferadi, M., Bakand, S., Orak, R.J., Mirkazemi, R., Penicillin dust exposure and penicillin resistance among pharmaceutical workers in Tehran, Iran. Int. J. Occup. Environ. Health 22(3), 218-223, 2016, doi: 10.1080/10773525.2016.1201238

Fent, K., Weston, A.A., Caminada, D., Ecotoxicology of human pharmaceuticals. Aquat. Toxicol. 76, 122–59, 2006.

Foureaux, A.F.S. E.O. Reis, Y. Lebron, V. Moreira, L. V. Santos, M.S. Amaral, L.C. Lange, Rejection of pharmaceutical compounds from surface water by nanofiltration and reverse osmosis, Sep. Purif. Technol. (2019). https://doi.org/10.1016/j.seppur.2018.11.018.

Gaw, S., Thomas, K.V., Hutchinson, T.H., Sources, impacts and trends of pharmaceuticals in the marine and coastal environment. Phil. Trans. R. Soc. B. 369, 20130572, 2014. doi:10.1098/rstb.2013.0572

Gros. M, Rodriguez-Mozaz. S, and Barcelό. D (2012). Fast and comprehensive multi-residue analysis of a broad range of human and veterinary pharmaceuticals and some of their metabolites in surface and treated waters by ultra-high-performance liquid chromatography coupled to quadupole-linear ion trap tandem mass spectrometry. Journal of chromatography A. 1248: 104–121.

Gwenzi, W., Chaukura, N., Noubactep, C., Mukome, F.N., 2017. Biochar-based water treatment systems as a potential low-cost and sustainable technology for clean water provision. J. Environ. Manag. 197, 732–749.

Heron, R.J.L., Pickering, F.C., Health effects of exposure to active pharmaceuticals ingredients (APIs). Occup. Med. 53, 357-362, 2003. doi:10.1093/kqg115

Houtman, C.J., Emerging contaminants in surface waters and their relevance for the production of drinking water in Europe. J. Integrative Sci. 7(4), 271–295, 2010. doi:10.1080/1943815X.2010.511648

Houtman, C.J. J. Kroesbergen, K. Lekkerkerker-Teunissen, J.P. van der Hoek, Human health risk assessment of the mixture of pharmaceuticals in Dutch drinking water and its sources based on frequent monitoring data, Sci. Total Environ. (2014). https://doi.org/10.1016/j.scitotenv.2014.07.022.

International Agency for Research on Cancer (2012) Pharmaceuticals: A review of human carcinogens. IARC Monographs on the evaluation of carcinogenic risks to humans Viol 100A, IARC, Leon, 2012.

Jayasuriya, D.C., Regulation of pharmaceuticals in developing countries: legal issues and approaches. WHO, Geneva, 1985.

Jones, O.A.H., Voulvoulis, N., Lester, J.N., Potential ecological and human health risks associated with the presence of pharmaceutically active compounds in the aquatic environment. Crit. Rev. Toxicol. 34, 335–50, 2004.

Kaczala, F., Blum, S.E., The occurrence of veterinary pharmaceuticals in the environment. A review. Curr. Analyt. Chem. 12(3), 169–182, 2016.

Kay. P, Hughes. S. R, Ault. J. R, Ashcroft. A. E and Brown. L. E (2017). Widespread, routine occurrence of pharmaceuticals in sewage effluent, combined sewer overflows and receiving waters. Environmental pollution 220 pp. 1447–1455.

Kibuye, F.A., Gall, H.E., Elkin, K.R., Swistock, B., Veith, T.L., Watson, J.E., Elliot, H.A., Occurrence, concentrations and risks of pharmaceutical compounds in private wells in central Pennsylvania. J. Environ. Qual. 48, 1057–1066, 2019. doi:10.2134/jeq2018.08.0301

Koopaei, N.N., Abdollahi, M., Health risks associated with pharmaceuticals in wastewater. DARU J. Pharm. Sci. 25, 9, 2017. doi:10.1186/s40199-017-0176-y

K’oreje. K. O, Dermeestere. K, DeWisdaere. P, Vergeyst. L, Dewulf. J and Van Langenhove. H (2012). From multi-residue screening to target analysis of pharmaceuticals in water: development of new approach based on magnetic sector mass spectrometry and application in the Nairobi River basin Kenya. Science of the Total Environment, 437, pp.153–164.

Kumar, A., Chang, B., Xagoraraki, I., Human health risk assessment of pharmaceuticals in water: Issues and challenges ahead. Int. J. Environ. Res. Public Health 7, 3929-3953, 2010. doi:10.3390/ijerph7113929

Kumar, A. I. Xagoraraki, Human health risk assessment of pharmaceuticals in water: An uncertainty analysis for meprobamate, carbamazepine, and phenytoin, Regul. Toxicol. Pharmacol. 57 (2010) 146–156. https://doi.org/10.1016/j.yrtph.2010.02.002.

Kümmerer, K., Pharmaceuticals in the environment - A brief summary. In: Pharmaceuticals in the Environment, K, Kümmerer (Ed.), pp. 3-21, Springer, Berlin, Heidelberg, 2008. doi.org/10.1007/978-3-540-74664-5_23

Kümmerer, K., Pharmaceuticals in the environment. Annu. Rev. Environ. Resour. 35, 57–75, 2010. doi: 10.1146/annurev-environ-052809-161223

Küster, A., Adler, N., Pharmaceuticals in the environment: scientific evidence of risks and its regulation. Phil. Trans. R. Soc. B. 369, 20130587, 2014. doi:10.1098/rstb.2013.0587

Lagesson,. A, Fahlman, J., Brodin, T., Fick, J., Jonsson, M., Byström, P., Bioaccumulation of five pharmaceuticals at multiple trophic levels in an aquatic food web - Insights from a field experiment. Sci. Tot. Environ. 568, 208–215, 2016. doi:10.1016/j.scitotenv.2016.05.026

Letsinger, S., Kay, P., Comparison of priotisation schemes for human pharmaceuticals in the aquatic environment. Environ. Sci. Pollut. Res. 26, 3479-3491, 2019. doi:10.1007/a11356-018-3834-9

Leung, H.W., Jin, L., Wei, S., Tsui, M.M.P., Zhou, B., Jiao, L., Cheung, P.C., Chun, Y.K., Murphy, M.B., Lam, P.W.S., Pharmaceuticals in tap water: Human health risk assessment of proposed monitoring framework in China. Environ. Health Perspect. 121, 839-846, 2013. doi:10.1289/ehp.1206244

Li. M, Sun. Q, Li. Y, Lv. M, Lin. L, Wu. Y, Ashfaq. M and Yu. C (2016). Simultaneous analysis of 45 pharmaceuticals and personal care products in sludge by matrix solid-phase dispersion and liquid chromatography tandem mass spectrometry. Anal Bioanal Chem 408: 4953–4964.

Li, N. K.W.K. Ho, G.G. Ying, W.J. Deng, Veterinary antibiotics in food, drinking water, and the urine of preschool children in Hong Kong, Environ. Int. (2017). https://doi.org/10.1016/j.envint.2017.08.014.

Licona, K.P.M. L.R. d. O. Geaquinto, J. V. Nicolini, N.G. Figueiredo, S.C. Chiapetta, A.C. Habert, L. Yokoyama, Assessing potential of nanofiltration and reverse osmosis for removal of toxic pharmaceuticals from water, J. Water Process Eng. (2018). https://doi.org/10.1016/j.jwpe.2018.08.002.

Liu, S., Zhao, H., Lehmler, H.J., Cai, X. and Chen, J., 2017. Antibiotic pollution in marine food webs in Laizhou Bay, North China: trophodynamics and human exposure implication. Environmental science & technology, 51(4), pp.2392–2400.

Lόpez-Serna. R, Kasprzyk-Hordera. B, Petrovic. M and Barcelό. D (2013). Multiresidue enantiomeric analysis of pharmaceuticals and their active mobilities in the Guadlquivir River basin (South Spain) by chiral liquid chromatography coupled with tandem mass spectrometry. Anal. Bioanal. Chem., 405: 5859–5873.

Malchi, T. Y. Maor, G. Tadmor, M. Shenker, B. Chefetz, Irrigation of root vegetables with treated wastewater: Evaluating uptake of pharmaceuticals and the associated human health risks, Environ. Sci. Technol. 48 (2014) 9325–9333. https://doi.org/10.1021/es5017894.

Maskaoni. Kand Zhou. J. L (2010). Colloids as a sink for certain pharmaceuticals in the aquatic environment. Environ. Sci. Pollut. Res. 17: 898-907.

Miller, T.H., Bury, N.R., Owen, S.F., MacRae. J.I., Baron, L.P., A review of the pharmaceutical exposome in aquatic fauna. Environ. Pollut. 239, 129–146, 2018. doi:10.1016/j.envpol.2018.04.012

Moldovan. Z, Chira. R and Alder. A. C (2009). Environmental exposure of pharmaceuticals and musk fragrances in the Somes River before and after upgrading the municipal wastewater treatment plant Cluj-Napoca, Romania. Environ. Sci. Pollut. Res. 16 (suppl 1):S46–S54.

Murdoch. K (2015). Pharmaceutical pollution in the environment: Issues for Australia, New Zealand and Pacific Island countries. www.ntn.org.au Accessed 19 December 2019.

Nikolaou. A, Meric. S and Fatta. D (2007). Occurrence patterns of pharmaceuticals in water and wastewater environments. Anal. Bioanal. Chem. 387: 1225–1234.

Nimmen, N.F.J., Poels, K..LC., Veulemans, H.A.F., Identification of exposure pathways for opioid narcotic analgesics in pharmaceutical production workers. Ann. Occup. Hyg. 50(7), 665–677, 2006. doi:10.1093/annhyg/mel028

Oliveira F.R., Patel A.K., Jaisi D.P., Adhikari S., Lud H., Khanal S.K. (2017) Environmental application of biochar: Current status and perspectives. Bioresource Technology 246: 110–122.

Oskarsson, H., Wiklund, A-KE., Thorsén, G., Danielsson, G., Kumblad, L., Community interactions modify the effects of pharmaceutical exposure: A microcosm study on responses to propranolol in Baltic Sea coastal organisms. PLoS ONE 9(4), e93774, 2014. doi:10.1371/journal.pone.0093774

Osorio. V, Larraňaga. A, Aceňa. J, Pérez. S and Barcelό (2016). Concentration and risk of pharmaceuticals in freshwater systems are related to the population density and the livestock units in Iberian Rivers. Science of the total environment 540: 267–277.

Paiga. P, Santos. L. H, Ramos. S, Jorge. S, Silva. J. G and Delerue-Matos. C (2016), Presence of pharmaceuticals in the Lis River (Portugal): sources, fate and seasonal variation, science of the total environment 573 pp 164–177.

Paltiel, O., Fedorova, G., Tadmor, G., Kleinstein, G., Maor, Y., Chefetz, B., Human exposure to wastewater-derived pharmaceuticals in fresh produce. A randomised controlled trial focusing on carbamazepine. Environ. Sci. Technol. 50, 4476–4482, 2016. doi:10.1021/acs.est.5b06256

Patel M., Kumar R., Kishor K., Mlsna T., Pittman Jr. C.U., Mohan D. (2019) Pharmaceuticals of Emerging Concern in Aquatic Systems: Chemistry, Occurrence, Effects, and Removal Methods. Chem. Rev. 119(6): 3510–3673.

Petrovska, B.B., Historical review of medicinal plants’ usage. Pharmacognosy Rev. 6(11), 1-5, 2013. doi:10.4103/0973-7847.95849

Pezzola, A., Sweet, C.M., Global pharmaceutical regulation: the challenge of integration for developing states. Globalisation and Health 12, 85, 2016. doi:10.1185/s12992-016-0208-2

Praveena, S.M., Rashid, M.Z.M., Nasir, F.A.M., Yee, W.S. and Aris, A.Z., 2019. Occurrence and potential human health risk of pharmaceutical residues in drinking water from Putrajaya (Malaysia). Ecotoxicology and environmental safety, 180, pp.549–556.

Prosser, R.S., Sibley, P.K., Human health risk assessment of pharmaceuticals and personal care products in plant tissue due to biosolids and manure amendments, and wastewater irrigation. Environ. Int. 75, 223–233, 2015. doi:10.1016/j.envint.2014.11.020

Rägo, L., Santoso, B., Drug regulation: History, present and future. In: Drug benefits and risks: International textbook for clinical pharmacology, C.J. van Boxtel., B, Santoso., I.R. Edwards (Eds), 2 edn, pp. 65–76. IOS Press, Uppsala, 2008.

Ragowska, J., Zimmermann, A., Muszyñska, A., Ratajczk, W., Wolska, L., Pharmaceutical household waste practices: Preliminary findings from a case study in Poland. Environ. Manag. 64, 97–106, 2019. doi:10.1007/s00267-019-01174-7

Ratanawijitrasin, S., Wondemagegnehu, E., Effective drug regulation - A multicountry study. WHO, Geneva, 2002.

Riva, F., Castiglioni, S., Fattore, E., Manenti, A., Davoli, E. and Zuccato, E., 2018. Monitoring emerging contaminants in the drinking water of Milan and assessment of the human risk. International journal of hygiene and environmental health, 221(3), pp.451–457.

Rosales E., Meijide J., Pazos M., Sanromán M.A. (2017) Challenges and recent advances in biochar as low-cost biosorbent: From batch assays to continuous-flow systems. Bioresource Technology, 246:176–192.

Sayadi, M.H. R.K. Trivedy, R.K. Pathak, Pollution of pharmaceuticals in environment, J. Ind. Pollut. Control. (2010).

Schulman, L.J., Sargent, E.V., Naumann, B.D., Faria, E..C, Dolan,. DG., John, P,. Wargo, J.P., A human health risk assessment of pharmaceuticals in the aquatic environment. Hum. Ecol. Risk Assess. 8(4), 657–680, 2002. doi:10.1080/20028091057141

Schwab, B.W. E.P. Hayes, J.M. Fiori, F.J. Mastrocco, N.M. Roden, D. Cragin, R.D. Meyerhoff, V.J. D’Aco, P.D. Anderson, Human pharmaceuticals in US surface waters: A human health risk assessment, Regul. Toxicol. Pharmacol. 42 (2005) 296–312. https://doi.org/10.1016/j.yrtph.2005.05.005.

Schwarzenbach, R.P., Escher, B.I., Fenner, K., Hofstetter, T.B., Johnson, C.A., Von Gunten, U., Wehrli, B., 2006. The challenge of micropollutants in aquatic systems. Science 313(5790), 1072–1077.

Sermejian, L., Shanableh, A., Semreen, M.H., Samarai, M., Human health risk assessment of pharmaceuticals in treated wastewater reused for non-potable applications in Sharjah, United Arab Emirates. Environ. Int. 121, 325–331, 2018. doi:10.1016/j.envint.2018.08.048

Sharma, B.M., Bečanová, J., Scheringer, M., Sharma, A., Bharat, G.K., Whitehead, P.G., Klánová, J. and Nizzetto, L., 2019. Health and ecological risk assessment of emerging contaminants (pharmaceuticals, personal care products, and artificial sweeteners) in surface and groundwater (drinking water) in the Ganges River Basin, India. Science of the Total Environment, 646, pp.1459–1467.

Sharma V.K., Yu X., McDonald T.J., Jinadatha C., Dionysiou D.D., Feng M. (2019) Elimination of antibiotic resistance genes and control of horizontal transfer risk by UV-based treatment of drinking water: A mini review. Front. Environ. Sci. Eng. 13(3): 37.

Shore, R.F., Taggart, M.A., Smits, J., Mateo, J., Richards, N.L., Frydays, S., Detection and drivers of exposure and effects of pharmaceuticals in higher vertebrates. Phil. Trans. R. Soc. B. 309, 20130570, 2014. doi:10.1098/rstb.2013.0570

Snyder, S.A. Occurrence, treatment, and toxicological relevance of EDCs and pharmaceuticals in water, in: Ozone Sci. Eng., 2008. https://doi.org/10.1080/01919510701799278.

Sorell, T.L., Approaches to the development of human health toxicity values for active pharmaceutical ingredients in the environment. Am. Assoc. Pharm. Scientists J. 18(1), 92-101, 2015. doi:10.1208/s12248-015-9818-5

Sorensen, J.P.R., Lapworth, D.J., Nkhuwa, D.C.W., Stuart, M.E., Gooddy, D.C., Bell, R.A., Chirwa, M., Kabika, J., Liemisa, M., Chibesa, M., Pedley, S., 2015. Emerging contaminants in urban groundwater sources in Africa. Water Res. https://doi.org/10.1016/j.watres.2014.08.002.

Szymonik, A., Lach, J., Malinska, K., Fate and removal of pharmaceuticals and illegal drugs present in drinking water and wastewater. Ecol. Chem. Eng. S. 24(1), 65–85, 2017. doi:10.1515/eces-2017-0006

Tarfiei, A. H. Services, H. Eslami, A.A. Ebrahimi, H. Services, of Environmental Health and Sustainable Development Pharmaceutical Pollution in the Environment and Health Hazards, (2018) 2–6.

Tian F., Ma S., Xu B., Hu X., Xing H., Liu J., Wang J., Li Y., Wang B., Jiang X. (2019) Photochemical degradation of iodate by UV/H2O2 process: Kinetics, parameters and enhanced formation of iodo-trihalomethanes during chloramination. Chemosphere 221: 292–300.

Togola. A and Budzinski. H (2007). Analytical development for analysis of pharmaceuticals in water samples by SPE and GC-MS. Anal. Bioanal. Chem. 388:627–635.

Tomasi, S., Roberts, K.J., Stull, J., Spiller, H.A., Mckenzie, L.., Pediatric exposures to veterinary pharmaceuticals. Pediatr. 139(3), e20161496, 2017. doi:10.1542/peds.2016-1496

Touraud, E., Roig, B., Sumpter, J.P., Coetsier, C., Drug residues and endocrine disruptors in drinking water: Risk for humans? Int. J. Hyg. Environ. Health 214, 437–441, 20 11. doi:10.1016/j.ijheh.2011.06.003

United States Environmental Protection Agency., Risk Assessment Guidance for Superfund Vol. 1. Human health evaluation manual (Part A). Office of Emergency and Remedial Response; Dec 1989. Report EPA/540/1-89/002, 20450, USEPA, Washington DC, (1989). https://www.epa.gov/sites/production/files/2015-09/documents/rags_a.pdf. [Accessed December 21 2019].

Vazquez-Roig. P, Andreu. V, Onghena. M, Blasco. C and Picό. Y (2011). Assessment of the occurrence and distribution of pharmaceuticals in a mediteranean wetland (L’Albufera, Valencia, Spain) LC-MS/MS. Anal. Bioanal. Chem. 400:1287–1301.

Verlicchi, P., Aukidy, M.A.l., Zambello, E., Occurrence of pharmaceutical compounds in urban wastewater: Removal, mass load and environmental risk after secondary treatment - A review. Sci. Tot. Environ. 429, 123–155, 2012. doi:10.1016/j.scitotenv.2012.04.028

Wang H., Hu H., Wang H., Zeng R.J. (2018) Impact of dosing order of the coagulant and flocculant on sludge dewatering performance during the conditioning process. Science of the Total Environment 643: 1065–1073.

Wang, S and Wang. H (2015). Adsorption behaviour of antibiotic in soil environment: A critical review. Front. Environ. Sci. Eng. 9(4): 565–574.

Wang, Z., Han, S., Cai, M., Du, P., Zhang, Z. and Li, X., 2020. Environmental behaviour of methamphetamine and ketamine in aquatic ecosystem: Degradation, bioaccumulation, distribution, and associated shift in toxicity and bacterial community. Water Research, 174, p.115585.

Wang Z., Srivastava V., Ambat I., Safaei Z., Sillanpää M. (2019) Degradation of Ibuprofen by UV-LED/catalytic advanced oxidation process. Journal of Water Process Engineering 31: 100808.

Webb, S., Ternes, T., Gibert, M., Olejniczak, K., Indirect human exposure to pharmaceuticals via drinking water. Toxicol. Lett. 142, 157–167, 2003. doi:10.1016/S0378-427(03)00071-7 [Accessed 21 December 2019].

Wilkinson, J.L., Hooda, P.S., Barker, J., Bartron, S., Swinden, J., Ecotoxic pharmaceuticals, personal care products, and other emerging contaminants: A review of environmental, receptor-mediated, developmental, and epigenetic toxicity with discussion of proposed toxicity to humans. Crit. Rev. Environ. Sci. Technol. 46(4), 336–381, 2015. doi:10.1080/10643389.2015.1096876

World Health Organisation., Pharmaceuticals in drinking-water. WHO, Geneva, 2012. https://www.who.int/water_sanitation_health/publications/2012/pharmaceuticals/en/

Williams, E.S. B.W. Brooks, Human Health Risk Assessment for Pharmaceuticals in the Environment: Existing Practice, Uncertainty, and Future Directions, in: 2012. https://doi.org/10.1007/978-1-4614-3473-3_8.

Williams. M, Ong. P. L, Williams. D. B and Kookana. R. S (2009). Pharmaceuticals and personal care products in the environment: Estimating the sorption of pharmaceuticals based on their distribution. Environmental toxicological and chemistry 28(12): 2572–2579.

Wu Y., Zhu S., Zhang W., Bu L., Zhou S. (2019) Comparison of diatrizoate degradation by UV/chlorine and UV/chloramine processes: Kinetic mechanisms and iodinated disinfection byproducts formation. Chemical Engineering Journal 375: 121972.

Yahya N., Aziza F., Jamaludin N.A., Mutali M.A., Ismail A.F., Salleh W.N.W., Jaafar J., Yusof N., Ludin N.A. (2018) A review of integrated photocatalyst adsorbents for wastewater treatment. Journal of Environmental Chemical Engineering 6: 7411–7425.

Yang, C., Barlow, S.M., Muldoon, J.K.L., Vitcheva, V., Boobis, A.R., Felter, S. P., Arvidson, K.B., Keller, D., et al., (2017). Thresholds of toxicological concern for cosmetics-related substances: New database, thresholds, and enrichment of chemical space. Food Chem. Toxicol. 109, 170-193, 2017. doi:10.1016/j. fct.2017.08.043

Zhang Y., Chu W., Yao D., Yin D. (2017) Control of aliphatic halogenated DBP precursors with multiple drinking water treatment processes: Formation potential and integrated toxicity. Journal of Environmental Sciences 58: 322–330.

Zhou. Y. F, Dai. C. M, Zhang. Y. L, Surampall. R. Y and Zhang. T. C (2011). A preliminary study on the occurrence and behaviour of carbamazepine (CBZ) in aquatic environment of Yangtze River Delta China. Environ Monit Assess 173: 45–53.

* Corresponding author: wgwenzi@yahoo.co.uk; wgwenzi@agric.uz.ac.zw