Читать книгу Assisted Reproduction Techniques - Группа авторов - Страница 168

Ultrasound scanning is a reliable noninvasive technique for assessing uterine size and shape, blood supply and endometrial thickness. Uterine artery blood flow may be assessed by Doppler scanning and quantified as the pulsatility index indicating degree of resistance to flow distal to the point of sampling. Endometrial biopsy may be performed with further assessment by histology and with immunohistologic techniques. Uterine distensibility is not easily assessable. A study assessed uterine characteristics in survivors of bone marrow transplant for acute lymphoblastic leukemia who had fractionated total body irradiation [7]. The patients were assessed after 3 months of a sex steroid regimen designed to mimic the normal hormonal milieu, achieving physiologic levels of serum estradiol and progesterone. There was an increase in uterine size, improvement in uterine artery blood flow and normal endometrial thickness. Whether or not pretreating patients before donor oocyte treatment in this manner improves pregnancy outcome remains unknown.