Читать книгу Assisted Reproduction Techniques - Группа авторов - Страница 58

This couple are fertile and don’t necessarily require assisted conception technology to conceive. Their reproductive options are either ICSI using ejaculated sperm followed by PGT on trophectoderm biopsy obtained from a day 5/6 blastocyst‐stage embryo or prenatal screening after natural conception and termination of an affected pregnancy. Using donor sperm from a cystic fibrosis–negative donor if they object to termination of pregnancy would be another option.

The expected chance of success of PGT per cycle is 40–50% when the female partner’s age is below 35 as in both case histories. Cost‐effectiveness of this treatment modality has been established [6].