Читать книгу Salivary Gland Pathology - Группа авторов - Страница 91

Sialadenosis, also known as sialosis, is a painless bilateral enlargement of the parotid glands and less commonly the submandibular and sublingual glands (see Chapter 6). It is typically bilateral and without inflammatory changes. No underlying mass is present. It has been associated with malnutrition, alcoholism, medications, and a variety of endocrine abnormalities, the most common of which is diabetes mellitus. In the early stages, there is gland enlargement but may progress to fatty replacement and reduction in size by late stages. By CT, there is slight increase in density of the entire gland in the early setting but the density decreases in the late stage when the gland is predominantly fatty. On T1 weighted MRI images in the early stage, the gland demonstrates a slight decrease in signal corresponding to the lower fat content and increased cellular component. T2 images show a slight increase in signal (Som and Curtin 1996; Bialek et al. 2006; Madani and Beale 2006a).