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SARCOIDOSIS

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Sarcoidosis is a granulomatous disease of unknown etiology (see Chapter 6). It typically presents with bilateral parotid enlargement. It may be an asymptomatic enlargement or may mimic a neoplasm with facial nerve palsy. The parotid gland usually demonstrates multiple masses bilaterally, which is a nonspecific finding and can also be seen with lymphoma, tuberculosis (TB) or other granulomatous infections, including cat‐scratch disease. There is usually associated cervical lymphadenopathy. The CT characteristics of the masses are slightly hypodense to muscle but hyperdense to the more fatty parotid gland. MRI also demonstrates nonspecific findings. Doppler US demonstrates hypervascularity, which may be seen with any inflammatory process. The classically described “panda sign” seen with uptake of 67Ga‐citrate in sarcoidosis is also not pathognomonic for this disease and may be seen with Sjögren syndrome, mycobacterial diseases, and lymphoma.

Salivary Gland Pathology

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