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Subcutis

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The subcutaneous tissue is mainly composed of fat and the primary cell type is the adipocyte. This tissue is highly innervated and vascularized. Historically, adipocytes’ only functions were thought to be energy storage, protection, and thermogenesis; however, new evidence suggests that adipocytes can play an important role in local and systemic immunity. Adipocytes express various innate immune receptors such as Toll‐like receptors and Nod‐like receptors. They can secrete inflammatory cytokines and can serve as antigen‐presenting cells for lymphocytes.

Diagnostics and Therapy in Veterinary Dermatology

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