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Barbed sutures have been used for a variety of human surgical procedures. The suture barbs are arranged in order to prevent pull out and eliminate the need for a knot at the end of the suture line. There are a few studies in the veterinary literature regarding barbed sutures, but their use is not widespread.

Triclosan is a broad spectrum antibacterial agent that has been added to many suture materials. Triclosan‐coated sutures inhibit growth of common skin flora and some methicillin‐resistant strains of Staphylococcus in vitro. Triclosan‐coated sutures are available for use in veterinary surgery; however, their efficacy in reducing surgical site infections is unclear and current studies have varying results (Rothenburger et al. 2002; Storch et al. 2004; Etter et al. 2013). Triclosan‐coated sutures were studied in ball pythons and no difference was seen in inflammatory response or surgical site infections (McFadden et al. 2011).

In addition to triclosan, chlorhexidine‐coated sutures are also available. Chlorhexidine diacetate is a biguanide antiseptic that exhibits a broad range of antimicrobial activity intended to inhibit the growth of Gram‐negative and Gram‐positive bacteria. Studies assessing the effectiveness of chlorhexidine are limited (Onesti et al. 2018), and at the time of this chapter preparation, no veterinary specific studies have been published.