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Invertebrates

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Anderson et al. (2010) examined five different suture materials in the skin of the sea hare (Aplysia californica). They found that braided silk produced the least amount of granuloma formation but aside from that, monofilament nylon, poliglecaprone, polydioxanone, and polyglactin 910 all had similar overall histology scores calculated on edema, inflammation, and granuloma formation.

A recent study described the tissue reactions in common earthworms (Lumbricus terrestris) to five different suture materials: chromic gut, monofilament nylon, polydioxanone, polyglactin 910, and silk. There was mild to moderate tissue reaction to all five suture materials and the results indicated polyglactin 910 was best with regards to tissue security and minimal reaction (Salgado et al. 2014).

While there would likely be few applications for the use of sutures in horseshoe crabs (Limulus polyphemus), one study found that polydioxanone produced the least amount of tissue reaction compared to nylon, poliglecaprone, polyglycolic 910, and silk (Krasner et al., unpublished data).

Surgery of Exotic Animals

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