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1.5 Osteoconductive characteristics of autografts
ОглавлениеAccording to the textbooks, autologous bone has the following properties: “osteoconductive, osteogenic, and osteoinductive.”3 Osteoconductive is the term used to describe the property of new bone being able to form on the surface.3 Therefore, osteoconductive materials can not only serve as a guide rail for bone regeneration in a defect of critical size, but also in bone augmentation. It is also a term, albeit unusual, for the property of implant surfaces that allows for the deposition of new bone without the formation of a fibrous layer.3,34 Osteoconductivity therefore first requires a surface. Once the transplanted bone has been partially resorbed, the remaining bone surface again becomes osteoconductive.100 Transplanted bone that remains after the initial resorption phase serves as a guide splint. Clinically, it is therefore common to dimension autologous bone, taking into account partial resorption. The reason why autologous bone clearly allows more bone formation than bone substitutes in the first weeks after transplantation in a pig mandibular defect16 remains a matter of speculation, but it is not particularly surprising that osteoblasts and their mesenchymal progenitors like the mineralized surface that they have produced themselves. In summary, the property osteoconductive can be confirmed for autologous bone through histology.