Читать книгу Bone and Soft Tissue Augmentation in Implantology - Группа авторов - Страница 36

This hereditary osteopathy, known as marble bone disease, shows a massive compression of cancellous bone and medullary spaces of the regular bone tissue caused by a genetic defect of the osteoclast function. Strong bone apposition without sufficiently simultaneous bone resorption compresses the medullary spaces so severely that hardly any vascularization remains possible. The bone then looks extremely white, like marble. Radiologically, the eponymous marble-like change in bone structure is also known as osteopetrosis. It also shows developmental disorders of the teeth, with enamel hypoplasia and crown and root malformations. High-grade sclerosis results in an increased risk of fracture of the entire skeleton, with a poor healing tendency of the bone, so that implant or augmentation therapy is absolutely contraindicated.⁶⁵ With this condition, single case reports show a high risk of osteomyelitis after implant placement.⁶¹