Читать книгу Computational Modeling and Simulation Examples in Bioengineering - Группа авторов - Страница 26

In the first part of this paper, literature survey on AAA biomechanics is reported including several aspects from experimental test, constitutive model, and ILT. Further, we presented our FE models, aimed at simulating and enhancing the computational study of the aneurismatic pathology. The combination of fluid and nonlinear structure modeling can give better understanding of the flow, pressure distribution, wall shear stress quantification, and effect of material properties and geometrical parameters. Computational methods have made patient‐specific analyses possible, a feature essential for understanding the progression of AAA in a particular patient. Finally, future clinical DSS is suggested by using DM approach. The main aim is to run predictive FSI model in order to estimate the risk of rupture and to use patient‐specific wall properties with calcium, tissue disease, and thrombus to overcome multiple level of uncertainties.

During the last two decades, significant efforts have been made in order to define a computational model which includes biomechanical and biological approach, but still a lot of clinical studies are necessary in order to make these computational studies real in everyday clinical practice.