Читать книгу A Practical Approach to Special Care in Dentistry - Группа авторов - Страница 185

 At this time, the main groups exposed to HIV infection are men who have sex with men, individuals who engage in risky heterosexual contact and parenteral drug users (the risk of perinatal transmission has declined dramatically in recent years)

 Two types of HIV, which share the same mechanism of action, have been identified: HIV‐1, which has a worldwide distribution, and HIV‐2, which is more common among African populations

 HIV infects cells with CD4+ receptors, mainly T‐cells, monocytes, tissue macrophages and dendritic cells. Within the cell, HIV replicates using the reverse transcriptase enzyme. The resulting DNA is imported into the cell nucleus and integrated. The infected cells release new virus particles by gemmation and the cells are ultimately destroyed