Читать книгу Essential Cases in Head and Neck Oncology - Группа авторов - Страница 59

 The presence of trismus in a patient with an oropharyngeal carcinoma reflects either perineural invasion or direct extension to the pterygoid muscles. The presence of either would predict aggressive behavior.

 It is important to completely and accurately assess a patient for surgical resectability prior to undertaking a surgical approach. A large tumor at risk of excision with positive margins obligates the patient to receive trimodality therapy if surgery is pursued.

 If there is concern regarding resectability, the patient is best treated nonoperatively to decrease morbidity.

 PET/CT after chemoradiation therapy must be obtained at least 12 weeks after completion of treatment to allow for accurate assessment of treatment response.

 A negative PET/CT at the completion of therapy is a reliable predictor of a complete response.

 Platinum‐based chemotherapy is the mainstay of head and neck SCC treatment, but there are other effective options for those patients who cannot receive platinum‐based agents.