Читать книгу Pathy's Principles and Practice of Geriatric Medicine - Группа авторов - Страница 517

Stool softeners such as dioctyl sodium sulfosuccinate and dioctyl calcium sulfosuccinate (docusate sodium) are reported to soften the stool, easing defecation. Despite the widespread use of these agents, there are no randomized controlled trials showing efficacy.⁴⁴ One study comparing dioctyl sodium sulfosuccinate with placebo showed no improvement in stool frequency or consistency.⁴⁵ Another study comparing dioctyl sodium sulfosuccinate with psyllium found psyllium to be superior.⁴⁶ The therapeutic use of stool softeners appears limited for the treatment of chronic constipation.