Читать книгу Veterinary Surgical Oncology - Группа авторов - Страница 144

Cryosurgery is a type of cytoreductive therapy that has been described for superficial skin tumors. Cryosurgery may be used in cases when surgery is not possible because of concurrent debilitating factors that prevent safe anesthesia. Cryosurgical ablation uses tissue freezing to destroy selected lesions. There are several methods of cryosurgery: open‐spray, closed‐spray, and cryoprobe method. Liquid nitrogen is sprayed on the tumor from a specified distance for 15–60 seconds. For malignant lesions, two to three freeze‐thaw cycles are recommended, while for benign lesions, two cycles are recommended. Before application, large vessels feeding the tumor may be ligated to prevent hemorrhage and to improve the freezing effect. Wounds heal by second intention. Patients should be closely monitored following cryosurgery to control the healing of the treated site and to treat possible complications. Reported complications include hemorrhage, pain, edema, depigmentation, tissue retraction, tendon rupture, alopecia, odor, and lameness (De Queiroz et al. 2008).