Читать книгу Genome Editing in Drug Discovery - Группа авторов - Страница 10

AAVAdeno-Associated VirusABEAdenosine Base EditorsADARAdenosine deaminases acting on RNAASOsAntisense oligonucleotidesCARChimeric Antigen ReceptorCas9CRISPR associated protein 9CBECytosine base editorsCRISPRClustered Regularly Interspaced Short Palindromic RepeatsCRISPRaCRISPR activationCRISPRiCRISPR interferencedCas9Dead Cas9DSBDouble strand DNA breakFACSFluorescence-activated cell sortingGEMMGenetically Engineered Mouse ModelHDRHomology Directed RepairiGEMInternational Genetically Engineered MachinesIPRIntellectual Property RightsLNPLipid Nano ParticlesNHEJNon-homologous end joiningPAMProtospacer adjacent motifspegRNAPrime editing guide RNARNAiRNA interferenceRNPRibonucleoproteinsgRNASingle guide RNAsiRNASmall interfering RNAshRNAShort hairpin RNATALENsTranscription activator-like effector nucleasesTGETherapeutic Genome EditingZFNsZinc finger nucleases