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2.2.4 Fluorescent Probes for Chemical and Biological Sensing

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Fluorescence analysis technology has attracted much attention in the fields of chemistry, biology, and environmental science due to low background noise, high sensitivity, excellent selectivity, and easy operation. However, the fluorescence of materials will be quenched in high concentration or aggregate state, which greatly reduces the detection signal. The practical application of the fluorescence sensing system is severely limited. Introducing a fluorescent probe with AIE characteristics into the sensing platform, on the one hand, can effectively avoid the fluorescence quenching effect; on the other hand, the sensitivity of the sensing system can be improved by the “off”‐to‐“on” process of the fluorescent signal. Figure 2.11 shows some molecules based on DSA applied in the fluorescent probes for chemical and biological sensing.

Handbook of Aggregation-Induced Emission, Volume 2

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