Читать книгу Drug Transporters - Группа авторов - Страница 57

OCTN1 expression in rat liver is responsive to the PPARα agonist clofibrate, although to a lesser degree than OCTN2 [82]. OCTN1 contains an intronic binding sequence for the transcription factor RUNX1, disruptions of which have implications in rheumatoid arthritis (RA) [4]. OCTN1 is regulated by PDZK1 [83].