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Contents

Оглавление

Cover

Title page

Copyright

Dedication

Preface

Acknowledgements

List of Contributors

1 Genomic and Epigenomic Biomarkers for Predictive Toxicity and Disease

2 MicroRNAs as Non-invasive Biomarkers of Toxicity and Chemical Hazard: Genomic and Epigenomic Biomarkers of Toxicology and Disease

10  3 EV (Extracellular Vesicle)-associated miRNAs as Biomarkers of Toxicity

11  4 Circulating miRNAs as Biomarkers of Toxic Heavy Metal Exposure

12  5 MicroRNA Biomarkers of Malignant Mesothelioma

13  6 Role of Non-coding RNAs in Innate Immune Responses Perturbed by Environmental Arsenic Exposure

14  7 Transcriptomics: Applications in Toxicology and Medicine

15  8 Network Biology for Biomarker Discovery and Therapy in Cancer

16  9 Epigenetic Biomarkers: Link to Maternal Exposure and Offspring Health Outcomes

17  10 The Role of Dynamic Epigenetic Changes in Modulating Homeostasis after Exposure to Low-dose Environmental Chemicals

18  11 Emerging Non-invasive Molecular Biomarkers for Early Cancer Detection

19  12 Aberrant DNA Methylation of Tumor Suppressor Genes and Oncogenes as Cancer Biomarkers

20  13 SMYD Protein Family as Promising Biomarkers for Cancer Diagnosis and Prognosis

21  14 Toward Precision Medicine: Epigenetic Alterations in Human Melanoma

22  15 Currents Trends and Future Perspectives in Our Epigenetic Signatures: What a Diet Can Trigger

23  16 Genetic and Epigenetic Biomarkers of Organophosphate Compounds, Dialkyl Phosphate Exposure, and Their Relation to Biological Effects

24  17 Genetic, Epigenetic, and Anatomical Factors in Agenesis and Development of Female Reproductive Tract

25  18 Cause or Consequence: Epigenomic DNA Methylation Changes in Arsenic-Mediated in Vitro Transformation of Human Prostate Cells

26  19 Epigenetic Regulation of Sex Determination and Toxicity in Nonmammalian Vertebrates

27  20 Characterization of Genomic and Epigenomic Biomarkers of Nanoparticle Toxicity Using the Zebrafish Model System

28  Index

29  End User License Agreement

Genomic and Epigenomic Biomarkers of Toxicology and Disease

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