Читать книгу Fundamentals of Fixed Prosthodontics - James C. Kessler - Страница 19

The prolonged presence of xerostomia, or dry mouth, is conducive to greater carious activity and is therefore extremely hostile to the margins of cast metal or ceramic restorations. Xerostomia can be caused by large doses of radiation in the oral region,³¹ lupus erythematosus,^22,32 or Sjogren syndrome, an autoimmune disease.³³ Sjogren syndrome frequently is first noticed and diagnosed by a dentist because of the xerostomia. ³⁴ It is frequently seen in conjunction with other autoimmune diseases, such as rheumatoid arthritis, lupus erythematosus, and scleroderma.³³

There are approximately 400 drugs capable of producing mild to severe xerostomia.^3,35 Anticholinergics, anorectics, and antihypertensives may produce this effect. Antihistamines comprise the largest group of such drugs, and chronic allergy sufferers who use them over a prolonged time may suffer from dry mouth.