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Structure and Complexity of Viral Genomes

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Despite the simplicity of expression strategies, the composition and structures of viral genomes are far more varied than those seen in the entire archaeal, bacterial, or eukaryotic domains. Nearly every possible method for encoding information in nucleic acid can be found in viruses. Viral genomes can be

 DNA or RNA

 DNA with short segments of RNA

 DNA or RNA with covalently attached protein

 single-stranded (+) strand, (–) strand, or ambisense (Box 3.2)

 double stranded

 linear

 circular

 segmented

 gapped

Principles of Virology

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