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BOX 3.2 TERMINOLOGY Important conventions: plus (+) and minus (–) strands

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mRNA is defined as the positive (+) strand, because it can be translated. A strand of DNA of the equivalent polarity is also designated as a (+) strand; i.e., if it were mRNA, it would be translated into protein.

The RNA or DNA complement of the (+) strand is called the (–) strand. The (–) strand cannot be translated; it must first be copied to make the (+) strand. Ambisense RNA contains both (+) and (–) sequences.

A color key for nucleic acids, proteins, membranes, cells, and more is located in the front of this book.


Principles of Virology

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