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Paradigms for Viral RNA Synthesis

Оглавление

Exact replicas of the RNA genome must be made for assembly of infectious viral particles. However, the mRNAs of most RNA viruses are not complete copies of the viral genome. The reproductive cycle of these viruses must therefore include a switch from mRNA synthesis to the production of full-length genomes. The majority of mechanisms for this switch regulate either the initiation or the termination of RNA synthesis.

Principles of Virology

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