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A Common Strategy for Viral Propagation

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The basic thesis of this textbook is that all viral propagation can be described in the context of three fundamental properties.

 Viral genomes are packaged inside particles that mediate their transmission from host to host.

 The viral genome contains the information for initiating and completing an infectious cycle within a susceptible, permissive cell.

 An infectious cycle includes attachment and entry, decoding of genome information, genome replication, and assembly and release of particles containing the genome.

 Viral propagation is ensured by establishment in a host population.

Principles of Virology

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