Читать книгу Essentials of Veterinary Ophthalmology - Kirk N. Gelatt - Страница 99

In many species, IOPs as measured with applanation tonometry in normal animals have been reported (Table 2.10). In humans and animals, short‐ and long‐term fluctuations in IOP occur for a variety of reasons (Table 2.11). Diurnal IOP variations generally occur in most species; in humans and dogs, the highest pressure occurs in the morning and the lowest in the afternoon. In contrast, the greatest IOPs occur during the day and the lowest IOPs are documented at night in the rabbit, cat, horse, and nonhuman primate. In glaucomatous canine patients, diurnal IOP fluctuations (as measured by tonometry) are typically much greater in comparison to normal dogs. Consequently, antiglaucoma medications administered once daily to dogs should be given in the evening to mitigate IOP spikes in the morning, when pressures are typically the greatest.