Читать книгу Canine and Feline Epilepsy - Luisa De Risio - Страница 237

Clinical signs occur from 10 min to 4 h after ingestion and include vomiting, diarrhoea, abdominal pain, hypersalivation, mydriasis, seizures, hyperthermia, obtunded mental status, tremors, hyperesthesia, ataxia, tachycardia and tachypnea (Gwaltney-Brant et al., 2000). In a study including 21 dogs with evidence of accidental 5-HTP ingestion, the minimum toxic dose reported was 23.6 mg/kg and the minimum lethal dose was 128 mg/kg (Gwaltney-Brant et al., 2000).