Читать книгу Basic Virology - Martinez J. Hewlett - Страница 50

There are two closely related types of herpes simplex virus: type 1 (facial, HSV‐1) and type 2 (genital, HSV‐2). Both establish latent infections in humans, and reactivation from such infections is important to virus spread. Some details concerning latent infection by HSV are discussed in Chapter 18 in Part IV. Different animal models demonstrate both general similarities and specific differences. These differences illuminate a major limitation of many animal models for human disease: A model often only partially reflects the actual course of disease in the natural host – in this case, in humans.