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Matthew B. Hamilton
Population Genetics
Читать книгу Population Genetics - Matthew B. Hamilton - Страница 1
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Оглавление
Страница 1
Table of Contents
List of Tables
List of Illustrations
Guide
Pages
Страница 7
Страница 8
Страница 9
Preface and acknowledgements
Страница 11
CHAPTER 1 Thinking like a population geneticist
1.1 Expectations
Parameters and parameter estimates
Inductive and deductive reasoning
1.2 Theory and assumptions
1.3 Simulation
Interact box 1.1 The textbook website
Chapter 1 review
Further reading
CHAPTER 2 Genotype frequencies 2.1 Mendel's model of particulate genetics
2.2 Hardy–Weinberg expected genotype frequencies
Interact box 2.1
Genotype frequencies for one locus with two alleles
2.3 Why does Hardy–Weinberg work?
2.4 Applications of Hardy–Weinberg
Forensic DNA profiling
Problem box 2.1 The expected genotype frequency for a DNA profile
Testing Hardy–Weinberg expected genotype frequencies
Box 2.1
DNA profiling
Assuming Hardy–Weinberg to test alternative models of inheritance
Problem box 2.2 Proving allele frequencies are obtained from expected genotype frequencies
Problem box 2.3 Inheritance for corn kernel phenotypes
2.5 The fixation index and heterozygosity
Interact box 2.2 Assortative mating and genotype frequencies
Box 2.2
Protein locus or allozyme genotyping
2.6 Mating among relatives
Impacts of non‐random mating on genotype and allele frequencies
Coancestry coefficient and autozygosity
Box 2.3 Locating relatives using genetic genealogy methods
Phenotypic consequences of mating among relatives
The many meanings of inbreeding
2.7 Hardy–Weinberg for two loci
Gametic disequilibrium
Physical linkage
Natural selection
Interact box 2.3 Gametic disequilibrium under both recombination and natural selection
Mutation
Mixing of diverged populations
Mating system
Population size
Interact box 2.4 Estimating genotypic disequilibrium
Chapter 2 review
Further reading
End‐of‐chapter exercises
Problem box answers Problem box 2.1 answer
Problem box 2.2 answer
Problem box 2.3 answer
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