Читать книгу Constitutional Oncogenetics - Noureddine Boukhatem - Страница 24

BRCA2 encodes a protein of 3418 amino acids and contains repeats of 39 amino acids that are critical for the binding of RAD51 recombinase (RAD51), a protein necessary for the repair of recombinant DNA. BRCA2 appears to have a more restricted role, largely limited to recombinant DNA repair and regulation of RAD51.