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HOW TO USE YOUR TEXTBOOK

FEATURES CONTAINED WITHIN YOUR TEXTBOOK

Standard icons are used throughout this book to denote different immunological molecules.

Your textbook is full of photographs, illustrations, and tables.

Self‐assessment review questions help you test yourself after each chapter.

REVIEW QUESTIONS

For each question, choose the ONE BEST answer or completion.

1 Which of the following applies uniquely with respect to B cells found in secondary lymphoid organs?present as precursor B cellsexpress only IgMterminally differentiate into plasma cellsundergo proliferation

2 The germinal centers found in the cortical region of lymph nodes and the peripheral region of splenic periarteriolar lymphatic tissue:support the development of immature B and T cellsfunction in the removal of damaged erythrocytes from the circulationact as the major source of stem cells and thus help maintain hematopoiesisprovide an infrastructure that on antigenic stimulation contains large populations of B lymphocytes and plasma cellsare the sites of natural killer T (NKT)‐cell differentiation

3 Which of the following sequences correctly describes lymphocyte migration from lymph nodes to blood?postcapillary venules, efferent lymphatic vessels, thoracic duct, vena cava, heartpostcapillary venules, afferent lymphatic vessels, thoracic duct, vena cava, heartpostcapillary venules, efferent lymphatic vessels, vena cava, thoracic duct, heartpostcapillary venules, afferent lymphatic vessels, vena cava, thoracic duct, heart

4 Clonal expansion of which of the following cells occurs following their direct interaction with the antigen for which they are specific?macrophagesbasophilsB cellsT cellsmast

The case icon indicates that you can find a correlated clinical case in Immunology: Clinical Case Studies and Disease Pathophysiology, edited by Warren Strober (NIAID/NIH) and Susan Gottesman (SUNY‐Downstate) (ISBN: 9780471326595; see http://bit.ly/ICCSDPsg).