Читать книгу Immunology - Richard Coico - Страница 67

A group of receptors specific for formylated peptides, such as N‐formylmethionine (fMet), are expressed at high levels on the membranes of polymorphonuclear and mononuclear phagocytes. fMet is specifically used for initiation of protein synthesis in bacteria. It is not used in cytosolic protein synthesis of eukaryotes. Synthetic formylated peptides have been shown to be chemotactic for phagocytes, leading to the concept of formylated peptides as PAMPs.