Читать книгу Essential Endocrinology and Diabetes - Richard I. G. Holt - Страница 52

 Mutations in DNA and chromosomal abnormalities can cause endocrine disease

 Meiosis is central to reproductive endocrinology

 Peptides and proteins are encoded by genes, which are stretches of genomic DNA

 Many protein hormones are synthesized as prohormones, which require post‐translational modification and processing before they become active

 Enzyme cascades synthesize hormones derived from amino acids and cholesterol

 Unlike peptide hormones, steroid hormones are not stored in cells but made on demand

 Many peptide hormones circulate free in the blood, unlike steroid or thyroid hormones, which associate with binding proteins