Читать книгу Handbook of Oral Pathology and Oral Medicine - S. R. Prabhu - Страница 134

 Apical periodontitis:Engorged blood vesselsIntense infiltration of neutrophils

 Periapical granuloma:Chronically inflamed granulation tissue around apex of a non‐vital tooth shows:Lymphocytes, macrophages, and plasma cells intermixed with neutrophils and proliferating epithelial cells (cell rests of Malassez) within the granulation tissue (Figure 3.2b)Cholesterol clefts with multinucleated giant cells, red blood cells, and areas of hemosiderin pigment (Figure 3.2c)Uninflamed layers of fibrous tissue at the peripheryPresence of osteoclasts

 Sequelae of periapical granuloma:Acute exacerbation can cause rapid enlargement of the lesion and may progress to abscess formationProliferation of the epithelial cell rests of Malassez associated with the inflammation may lead to the development of an inflammatory radicular cyst