Читать книгу Respiratory Medicine - Stephen J. Bourke - Страница 98

An increase in bicarbonate concentration causes a rise in pH. To compensate, ventilation is reduced in order to accumulate CO₂. This occurs despite the inevitable fall in PO₂. For this reason, however, scope for correction is limited; the compensatory fall in alveolar ventilation is modest and correction in pH may not be complete.

This pattern is seen where there has been administration of excessive alkali, loss of acid through vomiting or reabsorption of bicarbonate (e.g. in hypokalaemia).