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1 A LOOK AT CELLS AND TISSUES

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With very few exceptions, all living things are either a single cell or an assembly of cells. This chapter will begin to describe what a cell is, and further chapters will say much more. However, to begin with, we can briefly describe a cell as an aqueous (watery) droplet enclosed by a lipid (fatty) membrane. Cells are, with a few notable exceptions, small (Figure 1.1), with dimensions measured in micrometers (μm, 1 μm = 1/1000 mm). They are more or less self‐sufficient: a single cell taken from a human being can survive for many days in a dish of nutrient broth, and many human cells can grow and divide in such an environment. In 1838 the botanist Matthias Schleiden and the zoologist Theodor Schwann formally proposed that all living organisms are composed of cells. Their “cell theory,” which nowadays seems so obvious, was a milestone in the development of modern biology. Nevertheless, general acceptance took many years, in large part because the plasma membrane (Figure 1.2), the membrane surrounding the cell that divides the living inside from the nonliving extracellular medium, is too thin to be seen using a light microscope. Microorganisms such as bacteria, yeast, and protozoa exist as single cells. In contrast, the adult human is made up of about 30 trillion cells (1 trillion = 1012), which are mostly organized into collectives called tissues.

Cell Biology

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