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Details of Protein Synthesis

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In this section, we discuss the process of translation in more detail. First, we discuss reading frames, which determine which nucleotides in an mRNA are recognized as codons, and tRNA aminoacylation, which is responsible for correct matching of a tRNA with its cognate amino acid. Then, we discuss translation initiation, or how the 30S subunit finds the starting point of a coding sequence in the mRNA. Next, we discuss translation elongation, or what happens as the 70S ribosome moves along the mRNA, translating the information in the mRNA in the form of nucleotides into amino acids. Finally, we discuss how translation is terminated.

Snyder and Champness Molecular Genetics of Bacteria

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