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V.I. Dontsov. General system theory of aging. Special role of the immune system. 2019. – 320 p. Electronic edition. Figures – 57. Schemes – 4. Tables – 4. Formulas – 9.

Translation from Russian by the service of Springer Edit.


The monograph examines the general methodological problems of the aging of biological systems, debunking myths and cliches circulating in this area; modeling of the general aging process, highlighting the causes of aging, the main mechanisms, and their biological content, as well as consideration of the fundamental possibilities and directions of influence on this process.

A special place is occupied by the use of system analysis and consideration of integrative systems that combine hierarchically complex systems into a single whole, and the special role of the immune system, namely, that part of it, which is not responsible for immune phenomena proper, but regulates the interaction of various cell populations in the body. A single look at aging allows you to determine the possibilities and directions of influence on this process, and the allocation of aging syndromes, similar to those in common diseases, allows you to influence aging with conventional therapeutic agents.

The book is intended for specialists in the field of general biology and medicine, system analysis, for gerontologists and specialists in anti-age medicine and biology of aging, as well as for graduate students, teachers, and students of higher educational institutions, theorists and experimental studies.

General system theory of aging. Special role of the immune system

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