Читать книгу Anti-Aging Therapeutics Volume XV - A4M American Academy - Страница 18
HORMONE REPLACEMENT THERAPY History
ОглавлениеHormone replacement therapies with controlled substances such as testosterone and growth hormone have been used since many years. The first testosterone treatment of testosterone deficiency in adult men started around 1940 and since then, for more than 40 years growth hormone has been administered to treat short stature children and since 1985 with the safer, not contaminated recombinant growth hormone, product of biotechnology. In the latter 1980’s, the first clinical trial of adults with growth hormone deficiency were published, and since the beginning of the 1990s, growth hormone treatment of adult patients started in private medical practice.
The concept of Interventional Endocrinology acknowledges the fact that not everyone experiences symptoms of deficiency – relative or absolute - at the same levels. Therefore, taking a comprehensive medical history and physical can act to substantiate the application of replacement/supplementation protocols, in accordance with accepted standards of care. Clear documentation in this regard helps support the physician’s approach in treating the patient.