Читать книгу Anti-Aging Therapeutics Volume XV - A4M American Academy - Страница 19

To-date, no adverse effects of hormone replacement therapies administered to adults with diagnosed deficiency(ies) have been reported to the US FDA’s Adverse Event Reporting System (FAERS), the national database providing post-marketing safety surveillance for drug and therapeutic biologic products. Likewise, as of this writing, the US CDC’s Medication Safety Program contains no reports of adverse effects relating to HRT.

HGH therapy has been in use for over 40 years on adults and children⁸², with one of the best safety records in modern pharmacia and whose dose in adults is typically only 1/5 to 1/7 of the pediatric dose and under the strict supervision of an endocrinologist or anti-aging specialist. As of this writing, the US National Library of Medicine’s PubMed database lists over 100,000 peer-reviewed citations on HGH therapy; not a single death or permanent life threatening morbidity has been reported in its use of AGHD in otherwise healthy but AGHD patients.

The side effects of GH replacement therapy, if any, are usually minor and are reversible by decreasing the dose or in a few cases discontinuing the treatment. Significant side effects are rarely seen in clinical practice. Also, when the same total dose is divided daily over a week-long period (instead of administering 3 days a week) side effects are diminished or absent. If side effects do occur, it has been clinically demonstrated that they disappear with cessation of treatment.