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Type III – Delayed-onset, Mainly IgG-mediated Reactions

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The prime immune cell involved in these reactions is IgG. The reason for the delay in the reaction is because time is needed for the immune complex to form. The immune complex is made up of an antigen (food molecule) and an antibody, and triggers the release of inflammatory molecules from various tissues in the body, thereby causing inflammation. If these immune complexes are not eliminated from the body they can deposit in tissues and cause injury. The more immune complexes there are, and the more histamine and other ‘amines’ that are produced by the body, the more likely there will be tissue damage. An estimated 80 per cent of food intolerance reactions involve IgG.

The Food Intolerance Bible: A nutritionist's plan to beat food cravings, fatigue, mood swings, bloating, headaches and IBS

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