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Anterior Horn Cell Disease

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Relatively few diseases afflict the anterior horn. All are serious. The commonest is MND; spinal muscular atrophies, Kennedy’s disease, poliomyelitis and other viruses, notably West Nile are also causes. LMN signs of wasting and weakness develop. Amyotrophy is also a word used to describe wasting; it means myo (muscle) atrophy. Typically in all these diseases, initially at least, weakness can be highly selective. For instance, MND can present with weakness of one or two finger extensors. Neurophysiology is often diagnostic.

Neurology

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